Autogenous Osteochondral Graft Associated with IGF-1 in Induced Articular Cartilage Lesion in Rabbits
نویسندگان
چکیده
منابع مشابه
Pain perception in knees with circumscribed cartilage lesions is associated with intra-articular IGF-1 expression.
BACKGROUND Circumscribed cartilage defects are considered as prearthritic lesions and lead to differential intra-articular cytokine expression. Mechanisms of associated pain development and influence of smoking behavior are not yet fully understood in humans. PURPOSE This study aimed to reveal relations between synovial cytokine levels in knees with circumscribed cartilage defects and pain se...
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Background: The destruction of articular cartilage is the major cause of articular problems. The articular cartilage has little repair postertial due to lack of perichondrium and direct blood circulation. It is, therefore important to consider this phenomena in surgical treatments. One of the articular cartilage reconstructive surgeries is using Osteo-Chondral graft. The main purpose of this re...
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Cartilage has poor regenerative capacity. Donor site morbidity and interference with joint homeostasis should be considered when applying the autologous chondrocyte transplantation technique. The use of ectopically produced cartilage, derived from periosteum, might be a novel method to heal cartilage defects. Ectopic cartilage was produced by dissecting a piece of periosteum from the tibia of r...
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(ii) The Upper Middle Zone.-This contains rounded cells with branching irregular processes, often arranged in pairs. In addition to cytomembranes and mitochondria, many cells exhibit pinocytotic vesicles and large Golgi vacuoles, some of which open at the cell surface. The matrix immediately around each cell or between pairs contains fine fibres; the interfibrillar matrix between pairs often sh...
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Efforts to expand treatment options for articular cartilage repair have increasingly focused on the implantation of cell polymer constructs. Primary cells cultured from perichondrium, a chondrogenic tissue, were found to survive in vitro within a biodegradable porous polylactic acid matrix. These perichondrocyte-polylactic acid composite grafts were then implanted within osteochondral defects d...
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ژورنال
عنوان ژورنال: Acta Scientiae Veterinariae
سال: 2018
ISSN: 1679-9216
DOI: 10.22456/1679-9216.87212